GO:0004372 'glycine hydroxymethyltransferase activity'

Cvterm details 
Term id GO:0004372
Term name glycine hydroxymethyltransferase activity
Term definition Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
Comment 

Synonyms
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity EXACT EC:2.1.2.1
allothreonine aldolase activity EXACT EC:2.1.2.1
L-serine hydroxymethyltransferase activity EXACT EC:2.1.2.1
serine aldolase activity EXACT EC:2.1.2.1
serine hydroxymethylase activity EXACT EC:2.1.2.1
serine hydroxymethyltransferase activity EXACT EC:2.1.2.1
serine transhydroxymethylase activity EXACT EC:2.1.2.1
"5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1]
"allothreonine aldolase activity" EXACT [EC:2.1.2.1]
"L-serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1]
"serine aldolase activity" EXACT [EC:2.1.2.1]
"serine hydroxymethylase activity" EXACT [EC:2.1.2.1]
"serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1]
"serine transhydroxymethylase activity" EXACT [EC:2.1.2.1]

Relationships

Definition dbxrefs

Related dbxrefs
MetaCyc:GLYOHMETRANS-RXN
Reactome:REACT_100551 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Taeniopygia guttata"
Reactome:REACT_101143 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Canis familiaris"
Reactome:REACT_103730 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Oryza sativa"
Reactome:REACT_104026 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Plasmodium falciparum"
Reactome:REACT_105838 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Danio rerio"
Reactome:REACT_106100 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Gallus gallus"
Reactome:REACT_106938 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Taeniopygia guttata"
Reactome:REACT_108889 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Taeniopygia guttata"
Reactome:REACT_109080 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Oryza sativa"
Reactome:REACT_110497 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae"
Reactome:REACT_110666 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Arabidopsis thaliana"
Reactome:REACT_110712 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Xenopus tropicalis"
Reactome:REACT_110780 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mus musculus"
Reactome:REACT_111007 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Plasmodium falciparum"
Reactome:REACT_11108 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Homo sapiens"
Reactome:REACT_11159 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Homo sapiens"
Reactome:REACT_112625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mycobacterium tuberculosis"
Reactome:REACT_112714 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Staphylococcus aureus N315"
Reactome:REACT_113302 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Escherichia coli"
Reactome:REACT_113467 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Escherichia coli"
Reactome:REACT_114244 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Escherichia coli"
Reactome:REACT_114305 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Staphylococcus aureus N315"
Reactome:REACT_114385 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Staphylococcus aureus N315"
Reactome:REACT_114576 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mycobacterium tuberculosis"
Reactome:REACT_115121 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mycobacterium tuberculosis"
Reactome:REACT_1345 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Homo sapiens"
Reactome:REACT_30943 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Drosophila melanogaster"
Reactome:REACT_31482 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Gallus gallus"
Reactome:REACT_31564 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Rattus norvegicus"
Reactome:REACT_31591 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Rattus norvegicus"
Reactome:REACT_33927 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mus musculus"
Reactome:REACT_33932 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Plasmodium falciparum"
Reactome:REACT_34223 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Saccharomyces cerevisiae"
Reactome:REACT_77050 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Canis familiaris"
Reactome:REACT_77924 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Danio rerio"
Reactome:REACT_78152 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Rattus norvegicus"
Reactome:REACT_80167 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Saccharomyces cerevisiae"
Reactome:REACT_80412 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Oryza sativa"
Reactome:REACT_81468 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Bos taurus"
Reactome:REACT_82542 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Canis familiaris"
Reactome:REACT_84260 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Arabidopsis thaliana"
Reactome:REACT_86594 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Bos taurus"
Reactome:REACT_88214 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Drosophila melanogaster"
Reactome:REACT_88519 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mus musculus"
Reactome:REACT_89705 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Gallus gallus"
Reactome:REACT_90130 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Bos taurus"
Reactome:REACT_90410 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Drosophila melanogaster"
Reactome:REACT_91337 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Xenopus tropicalis"
Reactome:REACT_91776 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans"
Reactome:REACT_92924 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Caenorhabditis elegans"
Reactome:REACT_93345 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Schizosaccharomyces pombe"
Reactome:REACT_93885 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Xenopus tropicalis"
Reactome:REACT_95280 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Danio rerio"
Reactome:REACT_95373 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Schizosaccharomyces pombe"
Reactome:REACT_95737 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Arabidopsis thaliana"
Reactome:REACT_97896 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Schizosaccharomyces pombe"
Reactome:REACT_99194 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Caenorhabditis elegans"
RHEA:15484

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