Term id		GO:0004151
Term name		dihydroorotase activity
Term definition		Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+).
Comment

Synonyms
(S)-dihydroorotate amidohydrolase activity EXACT EC:3.5.2.3
carbamoylaspartic dehydrase activity EXACT EC:3.5.2.3
DHOase activity EXACT EC:3.5.2.3
dihydroorotate hydrolase activity EXACT EC:3.5.2.3
"(S)-dihydroorotate amidohydrolase activity" EXACT [EC:3.5.2.3]
"carbamoylaspartic dehydrase activity" EXACT [EC:3.5.2.3]
"DHOase activity" EXACT [EC:3.5.2.3]
"dihydroorotate hydrolase activity" EXACT [EC:3.5.2.3]

Relationships

Definition dbxrefs

Related dbxrefs
KEGG:R01993
MetaCyc:DIHYDROOROT-RXN
Reactome:REACT_100968 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Mus musculus"
Reactome:REACT_103707 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Schizosaccharomyces pombe"
Reactome:REACT_104176 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Saccharomyces cerevisiae"
Reactome:REACT_107004 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Plasmodium falciparum"
Reactome:REACT_109520 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Danio rerio"
Reactome:REACT_115876 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Gallus gallus"
Reactome:REACT_30522 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Bos taurus"
Reactome:REACT_32485 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Drosophila melanogaster"
Reactome:REACT_32516 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Dictyostelium discoideum"
Reactome:REACT_33026 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Caenorhabditis elegans"
Reactome:REACT_744 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Homo sapiens"
Reactome:REACT_78664 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Taeniopygia guttata"
Reactome:REACT_80045 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Rattus norvegicus"
Reactome:REACT_89075 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Canis familiaris"
Reactome:REACT_99796 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Staphylococcus aureus N315"

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